Complete nutrition for healthy aging
VitalFactors combines NAD support, amino acids, antioxidants, B vitamins, and vitamin D3 in a simple effervescent drink — five days on, two days off — designed to support vitality, focus, recovery, and healthy aging.
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What it supports
NAD precursors, CoQ10, and a complete B-complex provide the cofactors involved in how your cells make energy — the foundation of staying active.
Methylcobalamin B12 (8,333% DV), vitamin D3, and an amino-acid blend support focus and oxygen delivery to cells.
Resveratrol, Extramel® SOD, EGCG, vitamin C, and lycopene support antioxidant defense against the oxidative stress that accumulates over time.
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Made by Medical Doctors' Research
MDR — Medical Doctors' Research — has been formulating physician-grade supplements since 1984. VitalFactors is the formula MDR doctors built for adults who want to stay sharp, active, and consistent as they age. Used by board-certified surgeons, journalists, and 90-year-old film stars who still tour.
"I take VitalFactors and give it to my patients."
How it works
Two effervescent tablets, one glass of water, before a meal. Five days on, two days off.
Stir, let them dissolve, drink. The effervescent format puts the actives into solution your stomach can absorb directly.
Take your two tablets Monday through Friday, then take a two-day break on the weekend. The rhythm keeps the body responsive.
Most customers report feeling steadier energy and clearer focus inside the first month of consistent use.
Why this is different
A standard multivitamin covers basic vitamin deficiencies. VitalFactors adds the things that actually matter for healthy aging — NAD support, amino acids for recovery, and well-studied antioxidants — at meaningful doses.
Feature
VitalFactors
Typical multivitamin
Inside the formula
Plain-language descriptions of the non-obvious actives — the ingredients you don't typically find in a standard multivitamin. Full quantities are on the Supplement Facts panel below.
A clinically studied NAD⁺ precursor — supports cellular NAD⁺ levels involved in how cells make energy.
Branded red-grape polyphenol associated with healthy-aging research pathways.
Patented melon-derived superoxide dismutase enzyme — supports antioxidant defense against oxidative stress.
Coenzyme central to mitochondrial energy production — supports cellular energy.
A balanced amino-acid stack traditionally used by athletes for recovery and lean muscle support.
Supports focus and red blood cells, which carry oxygen to cells.
A complete B-vitamin panel involved in normal cellular metabolism and energy production.
Supports bone, mood, and immune health — the form your body uses most efficiently.
Antioxidant vitamin that supports immune function and collagen formation.
Polyphenol antioxidant that supports oxidative balance.
Antioxidant from tomatoes that supports a healthy cardiovascular system and healthy skin.
Concentrated polyphenols layered on top of resVida® for full-spectrum antioxidant support.
Brown seaweed extract rich in marine polysaccharides — studied for immune support.
Patented botanical complex (Nelumbo Nucifera) long valued in traditional botanical nutrition.
Supplement Facts
Serving size 2 tablets · 20 servings per container. Tap below to see the complete panel with every ingredient, amount, and % Daily Value.
Customer reviews
Real reviews from verified MDR customers — pulled from the live store, prioritizing feedback about staying active, recovery, and long-term consistency.
I have been taking VitalFactors for several years now and I can say I definitely see and feel the difference! I follow the recommended usage of five days on/two days off and it is working great for me. I now have my wife on this product and highly recommend it to anyone who wants to feel (and look) their best.
I’ve been using this product for years and have never been disappointed. The product does what it says,, gives energy and vitality.
At age 76, I feel my absolute best when I take Vital Factors. It provides me the energy I need and the mental alertness to accomplish my goals on a daily basis. Also helps me accomplish my exercise goals.
I've been taking/drinking Vital Factors for at least 20 years and never want to stop. The benefits are amazing! Thank you for making such a great vitamin drink.
I love this product so much, since I have been taking it I see a marked improvement of my hair and skin.
Been taking VitalFactors for two months. Love the taste so much that it has become my favorite drink. Hate that I’m supposed to skip 2 days a week but I follow the regimen and am feeling amazing.
Safety
VitalFactors is a nutritional formula made of vitamins, minerals, amino acids, and well-studied botanicals — not a drug — taken on a 5-on / 2-off cycle per the label. For most healthy adults it's a straightforward addition to a routine.
If you take prescription medications — especially blood thinners, diabetes medications, or hormone therapies — ask your physician or pharmacist before use. If you have kidney, liver, or gastrointestinal disease, or if you're pregnant or nursing, consult your physician first.
Contains soy isoflavones (a plant-based polyphenol). Free of gluten, dairy, eggs, fish, shellfish, tree nuts, peanuts, and animal ingredients.
Risk-free to try
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Subscriptions ship free in the US, usually within 24 hours; one-time orders ship for $6.95.
Don't feel a difference? Send it back within 60 days for a full refund of the product cost.
If you choose a subscription, cancel or pause from your account in two clicks. No phone call, no fees.
FAQ
VitalFactors is formulated as nutrition for healthy adults of any age, including older adults — used on a 5-on / 2-off cycle per the label. Many of our long-term customers are in their 70s, 80s, and 90s. If you have a chronic condition or take prescription medications, run the Supplement Facts panel by your physician first — that's just sensible practice with any supplement at any age.
Ready when you are
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